PhD fellowship: A toolbox to decipher glycerophospholipids (phosphatidylserine and phosphatidylinositol) roles in cellulo.

Dr. Sébastien Balieu
Université de Rouen
UMR 6014 CNRS COBRA, FRANCE

More details here

Two positions (Postdoctoral associate 12 months, and Research Engineer 18 months) in synthetic medicinal chemistry are available in the Anti-Infective Drug Discovery (AIDD) group of Pr Willand Nicolas at the research center Drugs and Molecules for Living Systems, (M2SV, INSERM, Institut Pasteur de Lille and University of Lille), specialized in drug discovery, medicinal chemistry, screening and pharmacokinetics.

Duties and responsabilities:

1/ Design and execute multi-step synthetic routes for the preparation of new fluoroquinolones in the context of the ANR collaborative program Detonator and small molecule boosters of nitroimidazole antibiotics in the context of the SATT Nord Smart-NIM project.

2/ Properly collect, interpret, manage and present research data

3/ Write reports and publications

4/ Actively participate in research discussions with members of the AIDD group in a highly collaborative way

5/ Mentor and supervise students

All applicants must have a PhD in synthetic medical / organic chemistry with extensive experience in organic synthesis. Skills in chemical biology and target identification through click-chemistry are preferred but not required.

Interested candidates should submit via email (nicolas.willand(at)univ-lille.fr) an application package consisting of cover letter, CV, short research summary and a list of three references. All files should be prepared in pdf.

GP2A (Group for the Promotion of Pharmaceutical chemistry in Academia) is delighted to announce that the 29th Annual GP2A Conference will take place online on August 25th to 27th 2021.

The full programme is available here.

Registration

To register for the conference, please use the registration form below (free registration but mandatory).

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    Abstract Submission

    Abstracts from conference registrants are invited for poster and oral presentation. Following review of all abstracts by the organising committee, a total of 8 abstracts will be selected for oral presentation (20 min).

    To submit your abstract, please download and complete the ‘abstract template and instructions file‘ below. Completed abstracts should be sent (in MS Word format) to gp2a2021ac@gp2a.org, with the email subject as ‘GP2A2021 Abstract submission‘. The deadline is 7th July 2021.

    Use the editable template by clicking on the section you would like to fill in and begin typing or overwriting. This should ensure that all your information is in the correct format.

    •             Please do not deviate from the formatting outlined in this template.

    •             Abstracts that deviate from this format will be returned for revision.

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    •             All abstracts must fit entirely onto one page. Be sure to underline the presenting author.

    Abstract template and instructions: download here.

    Dear friends, I hope everyone is well and healthy

    Please find the link for a PhD position available in my team, under my supervision, starting in september 2021,

    Thanks for disseminating in your networks and to your Master 2 students,

    Warm regards

    Dr. HDR Laurent PICOT
    Professor assistant in Biochemistry   UMRi CNRS 7266 LIENSs Team BCBS
    https://lienss.univ-larochelle.fr/Picot-Laurent-MCF-HDR

    Department of Biotechnology University of la Rochelle – France
    https://sciences.univ-larochelle.fr/departement-de-biotechnologies   French coordinator of the Franco-Brazilian Network on Natural Products FB2NP https://fb2np.recherche.univ-lr.fr/    Head of axis 1 theme 2 team Biotechnology and Chemistry of Bioresources for Health: Heterocycles and pigments for anticancer applications  

    Find below the videos of the GP2A Online Event that took place on Friday 5th March 2021.

    15:00 Opening – Prof. Pascal Marchand, University of Nantes, France
    About the GP2A network
    15:05 Lecture – Prof. Tom Coenye, Ghent University, Belgium
    Challenges in biofilm research: where do we stand and where are we going?
    15:50 Lecture – Prof. Concepción González-Bello, University of Santiago de Compostela, Spain
    Antibiotic adjuvants – A booming strategy to unlock bacterial resistance
    16:35 Lecture – Dr. Tim O’Sullivan, University College Cork, Ireland
    Synthesis and evaluation of novel quorum sensing inhibitors of Diffusible Signal Factor
    17:20 Prof. Pascal Marchand, University of Nantes, France
    Closing session

    Post-Doctoral position: Peptide/peptidomimetics synthesis for crop protection as an alternative to conventional chemical pesticides

    The Post-Doctoral fellow chosen for this position will take part in the EU-funded FETOPEN Network NoPest. NoPEST gathers research groups with complementary skills and infrastructures from five universities based in four EU countries and the associated state Israel together with SIPCAMOXON, a global company specialized in the synthesis, formulation and commercialization of active ingredients and (bio)chemicals for agriculture.

    Objective of the recruited Post-doctoral researcher: The Post-doctoral researcher enrolled in this position, will synthesize peptide and peptidomimetics with the aim to optimize the effectiveness of the peptides selected from the previous aptamers screening and from the biological evaluations carried out within the consortium partners. The applicant will be involved in the synthesis of unnatural scaffolds, i.e. non-natural amino acids (Aas), as for example fluorinated Aas, and in the synthesis of the designed peptide derivatives. The Post-doctoral researcher will be enrolled by the University of Paris-Saclay (https://www.universite-paris-saclay.fr/en) under the supervision of Prof. Sandrine Ongeri and Dr. Benoit Crousse (FLUOPEPIT/BioCIS, https://www.biocis.universite-paris-saclay.fr/?-FLUOPEPIT-&lang=en) and will participate to all the meetings and activities organized by the international consortium.

    University of Dundee recruits 1 Team leader and 4 Research Scientists (36 months) to work on a new drug discovery collaboration between Professor Alessio Ciulli and Almirall (a global biopharmaceutical company focused on skin health)

    Organic and medicinal chemistry – COSSBA team, UMR CNRS 5246 ICBMS, Lyon, France (Prof. Thierry Lomberget)

    Medicinal chemistry – University Paul Sabatier Toulouse 3, France (Dr Fatima El Garah)

    Organic chemistry – COBRA, UMR 6014, Rouen Normandy Univ., France (Dr Corinne Fruit and Prof. Thierry Besson)

    Bio-organic chemistry – COBRA, UMR 6014, Rouen Normandy Univ., France (Dr Ludovic Jean)

    Nanoparticle biological identity investigation – UMR CNRS 8612, Châtenay-Malabry, France (Dr Patrick Guenoun and Dr Frederic Gobeaux)

    Hybrid Hydrogels for sustained drug delivery – UMR CNRS 8612, Châtenay-Malabry, France (Prof. Laurent Corté and Prof. Sophie Norvez)

    The research team Drugs and Molecules for Living Systems, (INSERM, Institut Pasteur de Lille and University of Lille), specialized in drug discovery, medicinal chemistry, screening and pharmacokinetics (www.deprezlab.fr) is offering a 24-month postdoc position in the group of Pr Rebecca Deprez-Poulain. The candidate will be recruited by The Institut Pasteur de Lille, thanks to a PRECIDIAB grant, in our laboratory that gathers chemists and biologists to design new drugs in an inspiring and stimulating environment.

    The aim is to design, synthesize and perform multiparametric optimization of bioactive compounds acting on enzymes or receptors implicated in metabolic diseases and their co-morbidities.

    Find below the video of the 28th Annual GP2A Conference that took place online on Thursday 27th August 2020 at 15:00 CEST.

    15:00 Opening – Prof. Pascal Marchand, University of Nantes, France
    About the GP2A network
    15:15 Keynote Lecture – Prof. Barry Potter, University of Oxford, UK
    Steroid Sulfatase Inhibition: from Concept to Clinic and Beyond
    16:00 ECR Lecture – Dr Tina Seifert, University of Gothenburg, Sweden
    Modulating Sirtuin Activity – Development of SIRT2-selective inhibitors
    16:35 ECR Lecture – Dr Zoe Waller, University College London, UK
    Targeting i-motif DNA structures
    17:10 Dr Nicolas Primas, Aix-Marseille University, France
    Next GP2A Conference in Marseille, France – 25th-27th August 2021

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