french version :
press release of the French National Academy of Pharmacy published on March 30, entitled “COVID-19 and Drugs – There is an urgent need to restore confidence in Chemistry”.
Dear researchers,
Unfortunately, in this exceptional context of Covid-19 pandemic, GP2A board and the local organising committee of GP2A 2020 in La Rochelle took the decision to cancel the conference this year.
The current sanitary crisis does not allow an optimal preparation of the event and we do not know when all will go back to normal.
We hope your understanding and we will be delighted to welcome you at GP2A2021 Marseille – France on 25th-27th August 2021.
On behalf of GP2A committee
Keep safe, take care of you and your relatives
STAY AT HOME, PLEASE!!
Registration
To register for the conference, please use the registration portal: https://store.nottingham.ac.uk/conferences-and-events/conferences/schools-and-departments/pharmacy/27th-annual-gp2a-medicinal-chemistry-conference
Abstract Submission
Abstracts from conference registrants are invited for poster and oral presentation. Following review of all abstracts by the organising committee, a total of 6 abstracts will be selected for oral presentation.
To submit your abstract, please download complete the ‘abstract template and instructions file‘ below, and follow the instructions carefully. Completed abstracts should be sent (in MS Word format) to gp2a2019@gp2a.org, with the email subject as ‘GP2A2019 Abstract submission‘.
We are no longer considering abstracts for oral presentation – however if you would still like to present a poster at the conference, please submit your abstract as described above and complete your conference registration.
PhD/postdoctoral researcher speakers may be eligible for the conference travel award – click here to apply (deadline 31st July)!
Accommodation
The conference will be held at the East Midlands Conference Centre (EMCC), which is situated on University Park Campus (more information on the registration portal).
The most convenient accommodation is at the Orchard Hotel, which is adjacent to the EMCC.
There are a number of other accommodation options also available in the City Centre and Beeston, both of which are easy to travel to using Nottingham’s bus and tram network.
Social Events
On the afternoon of Thursday 22nd August, delegates will have the option to participate in one of two social events. These will run at the same time, so please select your preferred option during registration:
- Castle Rock brewery tour – An opportunity to take part in a tour of one of Nottingham’s most well-known real ale breweries. You will be transported to the city centre where the brewery is situated and take part in a tour lasting around 45 minutes, where you will learn about the facility and the brewing process. At the end of the tour there will be a chance to sample some of the brewery’s beers
- Wollaton Hall Tour – A guided tour of the historic Wollaton Hall (Wayne Manor in recent Batman films) and a chance to explore the extensive deer park. Please be aware that this tour involves over 300 steps and is unfortunately not suitable for those with limited mobility.
The 13th International Meeting on the Rapid Responses to Steroid Hormones (RRSH 2022) will be held from Tuesday, September 20, to Friday, September 23, 2022 at the Sorbonne, Paris (France). The meeting will be chaired by Yves Jacquot (University of Paris) and Matthias Barton (University of Zürich).
Information available here: https://www.jobs.ac.uk/job/COR844/research-assistant-associate
This is a full time, fixed term post available until 31 March 2023.
For informal enquiries, please contact Dr Celine Cano, celine.cano@ncl.ac.uk
Information about the Drug Discovery Unit can be found at: https://research.ncl.ac.uk/drugdiscovery/
Information about the Faculty of Medical Sciences is available at: https://www.ncl.ac.uk/medical-sciences/
Dans le cadre de l’Institut Convergences Plascan, un contrat doctoral est disponible pour une thèse de doctorat dans l’équipe “Petite Molécules pour Cibles Biologiques”, au sein du Centre de Recherche en Cancérologie de Lyon (UMR Inserm 1052 – CNRS 5286 – Université Lyon1 – Centre Léon Bérard).
Le sujet de thèse concerne le design, la synthèse et l’évaluation d’inhibiteurs non ATP-compétitifs de kinases. Il s’agira de développer des nouvelles molécules à activité anticancéreuses. Le candidat sera accueilli dans une équipe multidisciplinaire avec des expertises
en chimie médicinale, méthodes biophysiques pour les interactions kinase-petite molécule, biologie structurale, biochimie et tests cellulaires. Les approches rationnelles telles que la méthode par “fragments”, la modélisation et la cristallographie sont parmi les méthodologies envisagées. Les molécules seront aussi testées dans le cadre d’une collaboration (ANR) pour évaluer leur activité anti-virale sur différents coronavirus infectant l’homme.
Le candidat recherché devra avoir de solides compétences en chimie organique, et si possible en chimie médicinale. Le candidat aura la possibilité de se former à de multiples techniques et méthodologies en lien avec le design de molécules actives. Des connaissances en “drug design” seront un plus.
Le candidat devra commencer au plus tard le 1er Octobre 2022.
Mots clés : kinase – chimie médicinale – PROTAC – fragment – biologie structurale – interface
chimie-biologie
Contact pour candidater et envoyer un CV détaillé ainsi qu’une lettre de motivation
Isabelle Krimm
isabelle.krimm@univ-lyon1.fr
Version pdf ici.
DIVE : Development of Dual inhibitors Inspired by Vitamin E
as anti-inflammatory agents targeting 5-LO and mPGES-1
Contact: Dr Jean-Jacques HELESBEUX (jj.helesbeux@univ-angers.fr)
Location: SONAS, University of Angers (France)
Duration: 12 months (net salary per year: 28000€ approx.)
More details of the project and application guidelines are available here.
Project supervisor: Dr Jean-Jacques HELESBEUX (jj.helesbeux@univ-angers.fr)
Location: SONAS (Campus du Végétal) 42 rue Georges MOREL, 49070 BEAUCOUZE
To apply, please see all the details here.
Further information about the conference, including registration, program and invited speaker biographies, are available HERE.
For displaced researchers from Ukraine, support will be offered to attend the GP2A conference in August. If you have contacts from Ukraine who may be interested, please pass on this message and ask them to contact us at gp2a2022@gp2a.org.
Additional information: the deadline for abstract submission is postponed to 31st July 2022.
Sponsors: We are grateful to our sponsors. Click on their links to discover their products and services. ThermoFisher Scientific, Fáilte Ireland, CEM, Collaborative Drug Discovery (CDD), LabCup, BioPharma, Biotage, Almac Group, Key Organics, Labplan, Pharmaceuticals, Mason Technology, Lilly, GPE Scientific, Asynt, Fluorochem and RSC Medicinal Chemistry.
Laboratory:
EA 1155 – IICiMed (https://iicimed.univ-nantes.fr/en), University of Nantes, Institut de Recherche en Santé 2, 22 Boulevard Bénoni Goullin, 44200 Nantes – France
Contacts:
Prof. Pascal Marchand – pascal.marchand@univ-nantes.fr
Dr. Marc-Antoine Bazin – marc-antoine.bazin@univ-nantes.fr
Financial support:
French National Research Agency (ANR) collaborative project “TEXLEISH” (Targeting host-parasite interactions through the inhibition of EXcreted LEISHmania casein kinase 1) coordinated by Prof. Pascal Marchand.
Objectives of the thesis:
During the thesis project devoted to antiparasitic Drug Discovery, the candidate will be in charge of the design and the synthesis of imidazo[1,2-a]pyrazine-based heterocyclic compounds. The step-by-step pharmacomodulation will see the generation a novel chemical library to guide structure‐activity relationship study and will be supported by all the biological and in silico tools depicted above, and available through the partnership (EA 1155 – IICiMed, Institut Pasteur – Paris, UMR CNRS 8076 BioCIS Université Paris-Saclay).
As part of this project, the candidate will have to promote his (her) research work in consortium meetings, but also by participating to conferences. The completion of this PhD will give to the candidate a good expertise in drug development within a project at the interface of chemistry and biology.
Required profile:
The applicant, from university or engineer school, will possess a solid knowledge in organic and medicinal chemistry. He will be motivated to work closely with biological partners and collaborators involved in molecular modelling.
Application procedure:
All required documents are listed below:
• All degree certificates,
• Detailed CV,
• Cover Letter,
• Two recommendation letters (or contact information of at least 2 references).
Prof. Janine COSSY, ESPCI Paris – France from September-October 2021.
Contact and information here.
Contacts and information here.
Contacts and information here.